Publications and Presentations

Research publications

1. Gaurav Barve, Priyadarshini Sanyal and Ravi Manjithaya*. Septin localization and function during autophagy. Curr Genet 2018 Apr 12

2. S. N. Suresh, Aravinda K. Chavalmane, Malini Pillai, Veena Ammanathan, Vidyadhara DJ, Haorei Yarreiphang, Shashank Rai, Abhik Paul, James P Clement, Phalguni Anand Alladi and Ravi Manjithaya*. Modulation of Autophagy by a Small Molecule Inverse Agonist of ERRα Is Neuroprotective. Front. Mol. Neurosci. 2018 Apr 9;11:109.

3. Gaurav Barve, Shreyas Sridhar, Amol Aher, Mayurbhai H. Sahani, Sarika Chinchwadkar, Sunaina Singh, K. N. Lakshmeesha, Michael A. McMurray, Ravi Manjithaya*. Septins are involved at the early stages of macroautophagy in S. cerevisiae. J Cell Sci 2018 Feb 22;131(4). pii: jcs209098. doi: 10.1242/jcs.209098.

4. S. N. Suresh, Aravinda K. Chavalmane, Vidyadhara DJ, Haorei Yarreiphang, Shashank Rai, Abhik Paul, James P Clement, Phalguni Anand Alladi and Ravi Manjithaya*. A novel autophagy modulator 6-Bio ameliorates SNCA/α-synuclein toxicity. Autophagy 2017 28:0. doi: 10.1080/15548627.2017.1302045.

5. Piyush Mishra, Adrian N. Dauphinee, Carl Ward, Sovan Sarkar, Arunika H.L.A.N. Gunawardena, and Ravi Manjithaya*. Discovery of pan autophagy inhibitors through a highthroughput screen highlights macroautophagy as an evolutionarily conserved process across three eukaryotic kingdoms. Autophagy 2017 Sep 2;13(9):1556-1572. doi: 10.1080/15548627.2017.1339002.

6. Piyush Mishra, Shashank Rai and Ravi Manjithaya*. A dual luciferase based novel highthroughput assay to monitor autophagy in real time in yeast S. cerevisiae. Biochemistry and Biophysics Reports 11C (2017)138-146.



7. Chelur K. Rasmi, Sreedevi Padmanabhan, Kalyanee Shirlekar, Kanhirodan Rajan, Manjithaya R, Varsha Singh, and Partha Pratim Mondal. Integrated light-sheet imaging and flow-based enquiry (iLIFE) system for 3D in-vivo imaging of multicellular organism. Applied Physics Letters 111, 243702 (2017)

8. Rajasekhar K, Suresh SN, Manjithaya R*, Govindaraju T*. Rationally designed peptidomimetic modulators of aβ toxicity in Alzheimer's disease. Sci Rep. 2015 Jan 30;5:8139.

9. Dilipkumar S, Manjithaya R and Mondal PP. Multispectral Bayesian reconstruction technique for real-time two color fluorescence microscopy. RSC Adv., 2015,5, 13175-13183.

10. Rajasekhar K, Narayanaswamy N, Mishra P, Suresh SN, Manjithaya R and Govindaraju T. Synthesis of Hybrid Cyclic Peptoids and Identification of Autophagy Enhancer. ChemPlusChem 2014 79, 25–30.

11. Manjithaya R, Jain S, Farré JC, Subramani S.


Involvement of a yeast MAP kinase cascade in pexophagy, but not in non-selective or other selective autophagy pathways.

J Cell Biol. 2010 Apr 19;189(2):303-10.

This paper was highlighted/commented upon:

Deciding what to eat.

J Cell Biol. 2010 Apr 19;189(2):19.


Faculty of 1000 Biology: evaluations for Manjithaya R et al

12. Manjithaya R, Anjard C, Loomis W, Subramani S.


Unconventional secretion of Pichia pastoris Acb1 is dependent on GRASP protein, peroxisomal functions, and autophagosome formation.

J Cell Biol. 2010 Feb 22;188(4):537-46. Epub 2010 Feb 15.

This paper was highlighted/commented upon:

Unconventional secretion by autophagosome exocytosis.

Pfeffer SR. J Cell Biol. 2010 Feb 22;188(4):451-2.


Membrane trafficking: Mapping a new route.

Skinner MA. Nat Rev Mol Cell Biol. 2010 Mar;11, 234-235.


Protein Secretion: Unconventional Exit by Exophagy.

Abrahamsen H, Stenmark H. Curr Biol. 2010 May 11;20(9):R415

13. Farré JC, Mathewson RD, Manjithaya R, Subramani S.


Roles of Pichia pastoris Uvrag in vacuolar protein sorting and the phosphatidylinositol 3-kinase complex in phagophore elongation in autophagy pathways.

Autophagy. 2010 Jan;6(1):86-99.

14. Farré JC, Manjithaya R, Mathewson RD, Subramani S.


PpAtg30 tags peroxisomes for turnover by selective autophagy.

Dev Cell. 2008 Mar;14(3):365-76.

15. Nazarko TY, Polupanov AS, Manjithaya RR, Subramani S, Sibirny AA.


The requirement of sterol glucoside for pexophagy in yeast is dependent on the species and nature of peroxisome inducers.

Mol Biol Cell. 2007 Jan;18(1):106-18.

16. Manjithaya RR, Dighe RR.


The 3' untranslated region of bovine follicle-stimulating hormone beta messenger RNA downregulates reporter expression: involvement of AU-rich elements and transfactors.

Biol Reprod. 2004 Oct;71(4):1158-66.


1. Shikha Satendra Singh, Somya Vats, Amelia Yi-Qian Chia, Tuan Zea Tan, Shuo Deng, Mei Shan Ong, Frank Arfuso, Celestial T. Yap, Boon Cher Goh, Gautam Sethi, Ruby Yun-Ju Huang, Han Ming Shen, Manjithaya R* and Alan Prem Kumar*. Dual role of autophagy in hallmarks of cancer. Oncogene, 2017 Dec 19. doi: 10.1038/s41388-017-0046-6.

2. Sarika Chinchwadkar, Sreedevi Padmanabhan, Piyush Mishra, Sunaina Singh, Suresh S N, Somya Vats, Gaurav Barve, Veena A and Ravi Manjithaya*. Multifaceted housekeeping functions of autophagy. Journal of Indian Institute of Science. 2017 DOI 10.1007/s41745-016-0015-z Invited review

3. Rai S and Manjithaya R*. Fluorescence microscopy: A tool to study autophagy. AIP Advances 2015, 5, 084804. Invited review

4. Manjithaya R, Subramani S.


Autophagy: a new role in unconventional protein secretion.

Trends Cell Biol 2011 Feb;21(2):67-73. Invited review

5. Manjithaya R, Subramani S.


Role of autophagy in unconventional protein secretion.

Autophagy 2010 Jul 1;6(5):650-1. Invited review

6. Manjithaya R, Nazarko TY, Farré JC, Subramani S.


Molecular mechanism and physiological role of pexophagy.

FEBS Lett. 2010 Apr 2;584(7):1367-73. Invited review

7. Manjithaya RR, Dighe RR.


Regulation of Gonadotropins Synthesis.

Proc Indian Natn Sci Acad. 2006 72;(1):1-12.

Book Chapter

Singh, S and Manjithaya, R*. (2013). Role of the Golgi Complex and Autophagosome Biogenesis in Unconventional Protein Secretion. In: Hayat, MA. Autophagy: Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging. Elsevier. 105- 114.