Publications and Presentations

Publications fully or partially supported by Wellcome Trust/ DBT India Alliance (Independent PI):

Tiwari R#, Manzar N#, Bhatia V, Yadav A, Nengroo MA, Datta D, Carskadon S, Gupta

N, Sigouros M, Khani F, Poutanen M, Zoubeidi A, Beltran H, Palanisamy N, Ateeq B*. Androgen deprivation upregulates SPINK1 expression and potentiates cellular plasticity in prostate cancer. Nat Commun. 2020 Jan 20;11(1):384. doi:10.1038/s41467-019-14184-0. Publication

Bhatia V, Ateeq B*. Molecular Underpinnings Governing Genetic Complexity of ETS-Fusion-Negative Prostate Cancer. Trends Mol Med. 2019 Nov;25(11):1024-1038.
doi: 10.1016/j.molmed.2019.07.001. Publication 

Nigam S, Manzar N, Ateeq B*. Implications of the circular RNAs in localized prostate cancer. Ann Transl Med. 2019 Sep;7(Suppl 6):S195. doi:
10.21037/atm.2019.07.23. Publication 

Bhatia V#, Yadav A#, Tiwari R, Nigam S, Goel S, Carskadon S, Gupta N, Goel A, Palanisamy N, Ateeq B*. Epigenetic silencing of miRNA-338-5p and miRNA-421 drives SPINK1-positive prostate cancer. Clinical Cancer Research. 2018 Dec 26. pii: clincanres.3230.2018. doi: 10.1158/1078-0432.CCR-18-3230. *Corresponding Author.  Publication


Nunes JJ#, Pandey SK#, Yadav A#, Goel S, Ateeq B*. Targeting NF-kappa B signaling by Artesunate restores sensitivity of castrate-resistant prostate cancer cells to anti-androgens.  Neoplasia.  Volume 19, Issue 4, April 2017, 333-345. doi: 10.1016/j.neo.2017.02.002 .  *Corresponding Author.  Publication


Ateeq B*, Bhatia V, Goel S. Molecular Discriminators of Racial Disparities in Prostate Cancer. Trends in Cancer. 2016 Feb 11. doi: 10.1016/j.trecan.2016.01.005. *Corresponding Author. Publication


Tiwari R, Pandey SK, Goel S, Bhatia V, Shukla S, Jing X, Dhanasekaran SM, Ateeq B*. SPINK1 promotes colorectal cancer progression by downregulating Metallothioneins expression. Oncogenesis. 2015 Aug 10;4:e162. doi: 10.1038/oncsis.2015.23.  *Corresponding Author. Publication


Singh A, Nunes JJ, Ateeq B*. Role and therapeutic potential of G-protein coupled receptors in breast cancer progression and metastases. Eur J Pharmacol. 2015 May 14. pii: S0014-2999(15)30008-X. doi: 10.1016/j.ejphar.2015.05.011. *Corresponding Author. Publication 


Ateeq B*, Kunju LP, Carskadon SL, Pandey SK, Singh G, Pradeep I, Tandon V, Singhai A, Goel A, Amit S, Agarwal A, Dinda AK, Seth A, Tsodikov A, Chinnaiyan AM, Palanisamy N.  Molecular profiling of ETS and non-ETS aberrations in prostate cancer patients from northern India. Prostate. 2015 Jul 1;75(10):1051-62. doi: 10.1002/pros.22989. (Bushra Ateeq and Nallasivam Palanisamy contributed equally to this work). *Corresponding Author. Publication


Other Publications (Independent PI): 

Nur SM, Rath S, Ahmad V, Ahmad A, Ateeq B, Khan MI*. Nutritive vitamins as epidrugs. Crit Rev Food Sci Nutr. 2020 Feb 5:1-13. doi:


Gupta A, Nigam S, Avasthi I, Sharma B, Ateeq B, Verma S*. Caspase-3 mediated programmed cell death by a gold-stabilised peptide carbene. Bioorg Med Chem Lett.2019 Nov 1;29(21):126672. doi: 10.1016/j.bmcl.2019.126672. Epub 2019 Sep 12.PubMed PMID: 31570209.Publications

Khan MI*, Hamid A, Rath S, Ateeq B, Khan Q, Siddiqui IA, Adhami VM, Choudhry H, Zamzami MA, Mukhtar H. AKT inhibition modulates H3K4 demethylase levels in PTEN null prostate cancer. Mol Cancer Ther. 2018 Nov 16. pii: molcanther.0141.2018. doi: 10.1158/1535-7163.MCT-18-0141. Publication


Khan MI*, Al Johani A, Hamid A, Ateeq B, Manzar N, Adhami VM, Lall RK, Rath S,  Sechi M, Siddiqui IA, Choudhry H, Zamzami MA, Havighurst TC, Huang W, Ntambi JM, Mukhtar H. Pro-proliferative function of adaptor protein GRB10 in prostate carcinoma. FASEB J. 2018 Oct 31:fj201800265RR. doi: 10.1096/fj.201800265RR. Publication


Agarwal AK, Singh AP, Gupta T, Agarwal RA, Sharma N, Rajput P, Pandey SK, Ateeq BMutagenicity and Cytotoxicity of Particulate Matter Emitted from Biodiesel-Fueled Engines. Environ Sci Technol. 2018 Dec 18;52(24):14496-14507. doi: 10.1021/acs.est.8b03345.  Publication


Kumar N, Tyeb S, Manzar N, Behera L, Ateeq B, Verma V*. Entropically driven controlled release of paclitaxel from poly(2-ethyl-2-oxazoline) coated maghemite nanostructures for magnetically guided cancer therapy. Soft Matter. 2018 Aug 21;14(31):6537-6553. doi: 10.1039/c8sm01220b. Publication


Agarwal AK*, Ateeq B, Gupta T, Singh AP, Pandey SK, Sharma N, Agarwal RA, Gupta NK, Sharma H, Jain A, Shukla PC. Toxicity and mutagenicity of exhaust from compressed natural gas: Could this be a clean solution for megacities with mixed-traffic conditions? Environ Pollut. 2018 Aug;239:499-511. doi: 10.1016/j.envpol.2018.04.028. Publication


Singh A, Srivastava N, Amit S, Prasad S, Misra M, Ateeq B*. Association of AGTR1 (A1166C) and ACE (I/D) polymorphisms with Breast Cancer risk in North Indian population. Translational Oncology (vol 11(2), p233–242 April  2018.  *Corresponding Author.  Publication


Mishra G, Bhattacharyya S, Bhatia V, Ateeq B, Sharma A, Sivakumar S*. Direct Intra-nuclear Anticancer Drug Delivery via Polydimethylsiloxane Nanoparticles: In Vitro and In Vivo Xenograft Studies. ACS Appl Mater Interfaces.    2017 Sep 13. doi: 10.1021/acsami.7b08806. Publication


 Wang X, Qiao Y, Asangani IA, Ateeq B, Poliakov A, Cielik M, Pitchiaya S, Chakravarthi BVSK, Cao X, Jing X, Wang CX, Apel IJ, Wang R, Tien JC, Juckette KM, Yan W, Jiang H, Wang S, Varambally S, Chinnaiyan AM*. Development of Peptidomimetic Inhibitors of the ERG Gene Fusion Product in Prostate Cancer. Cancer Cell, 31, 1–17, April 10, 2017. doi: Publication


 Agarwal RA*, Gupta NK, Singh R, Nigam S, Ateeq B. Ag/AgO Nanoparticles Grown via Time Dependent Double Mechanism in a 2D Layered Ni-PCP and Their Antibacterial Efficacy.  Scientific Reports. 2017, 7: 44852. doi:10.1038/srep44852. Publication


Publications before Independent Position (Twenty Six) :

  • Khan AP, Rajendiran TM, Ateeq B, Asangani IA, Athanikar JN, Yocum AK, Mehra R, Siddiqui J, Palapattu G, Wei JT, Michailidis G, Sreekumar A, Chinnaiyan AM. The role of sarcosine metabolism in prostate cancer progression. Neoplasia. 2013 May; 15(5):491-501. Publication


  • Wu YM, Su F, Kalyana-Sundaram S, Khazanov N, Ateeq B, Cao X, Lonigro RJ, Vats P, Wang R, Lin SF, Cheng AJ, Kunju LP, Siddiqui J, Tomlins SA, Wyngaard P, Sadis S, Roychowdhury S, Hussain M, Feng FY, Zalupski MM, Talpaz M, Pienta KJ, Rhodes DR, Robinson DR, Chinnaiyan AM. Identification of Targetable FGFR Gene Fusions in Diverse Cancers. Cancer Discov. 2013 Apr 4.  Publication


  • Asangani IA, Ateeq B, Cao Q, Dodson L, Pandhi M, Kunju LP, Mehra R, Lonigro RJ, Siddiqui J, Palanisamy N, Wu YM, Cao X, Kim JH, Zhao M, Qin ZS, Iyer MK, Maher CA, Kumar-Sinha C, Varambally S, Chinnaiyan AM. Characterization of the EZH2-MMSET histone methyltransferase regulatory axis in cancer. Mol Cell. 2013 Jan 10;49(1):80-93). Publication


  • Wang R, Asangani IA, Chakravarthi BV, Ateeq B, Lonigro RJ, Cao Q, Mani RS, Camacho DF, McGregor N, Schumann TE, Jing X, Menawat R, Tomlins SA, Zheng H, Otte AP, Mehra R, Siddiqui J, Dhanasekaran SM, Nyati MK, Pienta KJ, Palanisamy N, Kunju LP, Rubin MA, Chinnaiyan AM, Varambally S.  Role of Transcriptional Co-Repressor CtBP1 in Prostate Cancer Progression. Neoplasia. Oct. 2012Vol. 14(10): 905-914. Publication


  • Grasso CS*, Wu YM*, Robinson DR*, Cao X, Dhanasekaran SM, Khan AP, Quist MJ, Jing X, Lonigro RJ, Brenner JC, Asangani IA, Ateeq B, Chun SY, Siddiqui J, Sam L, Anstett M, Mehra R, Prensner JR, Palanisamy N, Ryslik GA, Vandin F, Raphael BJ, Kunju LP, Rhodes DR, Pienta KJ, Chinnaiyan AM, Tomlins SA. The Mutational Landscape of Lethal Castrate Resistant Prostate Cancer. Nature. 2012 Jul 12; 487(7406):239-43. Publication


  • Ateeq B, Vellaichamy A, Tomlins SA, Wang R, Cao Q, Lonigro RJ, Pienta KJ, Varambally S. Role of Dutasteride in Pre-Clinical ETS- Fusion Positive Prostate Cancer Models. Prostate. 2012 Mar 13. doi: 10.1002/pros.22509. Publication


  • Robinson DR*, Kalyana-Sundaram S*, Wu YM, Shankar S, Cao X, Ateeq B, Asangani IA, Iyer M, Maher CA, Grasso CS, Lonigro RJ, Quist M, Siddiqui J, Mehra R, Jing X, Giordano TJ, Sabel MS, Kleer CG, Palanisamy N, Natrajan R, Lambros MB, Reis-Filho JS, Kumar-Sinha C, Chinnaiyan AM.  Functionally Recurrent Rearrangements of the MAST Kinase and Notch Gene Families in Breast Cancer. Nature Medicine. 2011 Nov 20; 17(12):1646-51. Publication


  • Cao Q, Mani RS, Ateeq B, Dhanasekaran SM, Asangani IA, Prensner JR, Kim JH, Brenner JC, Jing X, Cao X, Wang R, Li Y, Dahiya A, Wang L, Pandhi M, Lonigro RJ, Wu YM, Tomlins SA, Palanisamy N, Qin Z, Yu J, Maher CA, Varambally S, Chinnaiyan AM. Coordinated Regulation of Polycomb Group Complexes Through microRNAs in Cancer. Cancer Cell. 2011 Aug 16; 20(2):187-99. Publication


  • Brenner JC*, Ateeq B*, Li Y, Yocum AK, Cao Q, Asangani IA, Patel S, Wang X, Liang H, Yu J, Palanisamy N, Siddiqui J, Yan W, Cao X, Mehra R, Sabolch A, Basrur V, Lonigro RJ, Yang J, Tomlins SA, Maher CA, Elenitoba-Johnson KS, Hussain M, Navone NM, Pienta KJ, Varambally S, Feng FY, Chinnaiyan AM. Rationale for Inhibition of Poly(ADP-Ribose) Polymerase in ETS Gene Fusion Positive Prostate Cancer. Cancer Cell. 2011 May 17; 19(5):664-78. (*Equal contribution first author). Featured on Cover.  Publication


  • Ateeq B, Tomlins SA, Laxman B, Asangani IA, Cao Q, Cao X, Li Y, Wang X, Feng FY, Pienta KJ, Varambally S, Chinnaiyan AM. Therapeutic targeting of SPINK1-positive prostate cancer. Science Translational Medicine. 2011 Mar 2; 3(72):72ra17. Publication


  • Wang XS*, Shankar S*, Dhanasekaran SM*, Ateeq B, Sasaki AT, Jing X, Robinson D, Cao Q, Prensner JR, Yocum AK, Wang R, Fries DF, Han B, Asangani IA, Cao X, Li Y,  Omenn GS, Pflueger D, Gopalan A, Reuter VE, Kahoud ER, Cantley LC, Rubin MA, Palanisamy N, Varambally S, Chinnaiyan AM. Characterization of KRAS Rearrangements in Metastatic Prostate Cancer. Cancer Discovery. 2011 Jun 1;1(1):35-43. Publication


  • Rabbani SA, Ateeq B, Arakelian A, Valentino ML, Shaw DE, Dauffenbach LM, Kerfoot CA, Mazar AP. An anti-urokinase receptor (uPAR) antibody (ATN-658) blocks prostate cancer invasion, migration, growth and experimental skeletal metastasis in vitro and in vivo. Neoplasia. 2010 Oct. 12(10): 778–88. Featured on Cover.  Publication


  • Palanisamy N*, Ateeq B*, Kalyana-Sundaram S*, Pflueger D, Ramnarayanan K, Shankar S, Han B, Cao Q, Cao X, Suleman K, Kumar-Sinha C, Dhanasekaran SM, Chen YB, Esgueva R, Banerjee S, LaFargue CJ, Siddiqui J, Demichelis F, Moeller P, Bismar TA, Kuefer R, Fullen DR, Johnson TM, Greenson JK, Giordano TJ, Tan P, Tomlins SA, Varambally S, Rubin MA, Maher CA, Chinnaiyan AM.  Rearrangements of the RAF kinase pathway in prostate cancer, gastric cancer and melanoma. Nature Medicine. 2010 Jul; 16 (7):793-8. (*Equal contribution first author). Publication


  • Ateeq B, Tomlins SA, Chinnaiyan AM. AGTR1 as a therapeutic target in ER-positive and ERBB2-negative breast cancer cases. Cell Cycle. 2009 Dec; 8(23):3794-5. Publication


  • Rhodes DR*, Ateeq B*, Cao Q*, Tomlins SA*, Mehra R, Laxman B, Kalyana-Sundaram S, Lonigro RJ, Helgeson BE, Bhojani MS, Rehemtulla A, Kleer CG, Hayes DF, Lucas PC,  Varambally S, Chinnaiyan AM. AGTR1 over-expression defines a subset of breast ancer and confers sensitivity to losartan, an AGTR1 antagonist. Proc Natl Acad Sci. 2009 Jun 23; 106(25):10284-9. (*Equal contribution first author). Publication


  • Varambally S, Cao Q, Mani RS, Shankar S, Wang X, Ateeq B, Laxman B, Cao X, Jing X, Ramnarayanan K, Brenner JC, Yu J, Kim JH, Han B, Tan P, Kumar-Sinha C, Lonigro RJ, Palanisamy N, Maher CA, Chinnaiyan AM. Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer. Science. 2008, 12;322(5908):1695-9. Publication


  • Ateeq B, Unterberger A, Szyf M, Rabbani SA. Rabbani. Pharmacological inhibition of DNA methylation induces pro-invasive and pro-metastatic genes in vitro and in vivo. Neoplasia. 2008; 10(3):266-78. Publication


  • Sen S, Ateeq B, Sharma H, Datta P, Gupta SD, Bal S, Kumar A, Singh N. Molecular profiling of genes in squamous cell lung carcinoma in Asian Indians. Life Sciences. 2008; 82(13-14):772-9Publication


  • Ateeq B*, Abul Farah M, Ahmad W. Evidence of apoptotic effects of 2,4-D and butachlor on walking catfish, Clarias batrachus, by transmission electron microscopy and DNA degradation studies. Life Sciences.2006;78(9):977-86. *Corresponding Author.  Publication


  • Farah MA, Ateeq B, Ahmad W. Antimutagenic effect of neem leaves extract in freshwater fish, Channa punctatus evaluated by cytogenetic tests. Science of Total Environment. 2006; 364(1-3):200-14. Publication


  • Ateeq B*, Farah MA, Ahmad W. Detection of DNA damage by single cell gel electrophoresis in 2,4-D and butachlor exposed erythrocytes of Clarias batrachus. Ecotoxicology and Environmental Safety. 2006; 62(3):348-54. *Corresponding Author.   Publication


  • Farah MA, Ateeq B, Ali MN, Sabir R, Ahmad W. Studies on lethal concentrations and toxicity stress of some chlorinated xenobiotics on non–target organisms. Chemosphere. 2004; 55:257-265. Publication


  • Farah MA, Ateeq B, Ali MN, Ahmad W. Evaluation of genotoxicity of PCP and 2,4-D by micronucleus test in freshwater fish Channa punctatus. Ecotoxicology and Environmental Safety. 2003; 54(1): 25-29. Publication


  • Ateeq B, Farah MA, Ali MN, Ahmad W. Induction of micronuclei and erythrocyte alterations in the catfish Clarias batrachusby 2,4-dichlorophenoxyacatic acid and butachlor. Mutation Research. 2002; 518(2): 135-144. Publication


  • Ateeq B, Farah MA, Ali MN, Ahmad W. Clastogenicity of pentachlorophenol, 2, 4-D and butachlor evaluated by Allium root tip test. Mutation Research. 2002; 514: 105-113. Publication


  • Ahmad W, Ali MN, Farah MN, Ateeq B. Computerized automated morphometric assay including frequency estimation of pentachlorophenol induced nuclear anomalies (micronuclei) in catfish Heteropneustes fossilis. Chromosoma. 2002; 110: 570-574. Publication