Publications and Presentations

Publications:

1. Alexander S, George J, Korula A, Vijayakumar TS, David VG, Mohapatra A, Valson AT, Jacob S, Kakde S, Koshy PM, Rajan G, Matthai S, Jeyaseelan V, Ponnusamy B, Cook T, Pusey C, Daha M, Feehally J, Barratt J, Varughese S. The first South Asian five-year prospective longitudinal observational cohort study and biomarker evaluation investigating the unusual clinical course and risk profile of IgA Nephropathy among Indians from the single largest private not-for-profit tertiary healthcare institute in South India- GRACE IgANI Cohort (Glomerular Research And Clinical Experiments- IgA Nephropathy in Indians). (submitted for peer review to BMJ Open).

2. Cunha C, Alexander S, Ashby D, Lee J, Chusney G, Cairns T, Lightstone L. Hydroxycloroquine blood concentration in lupus nephritis: a determinant of disease outcome? Nephrol Dial Transplant. 2017 Nov 23. doi: 10.1093/ndt/gfx318. [Epub ahead of print].

3. Jagdish K, Jacob S, Varughese S, David VG, Mohapatra A, Valson AT, Kakde ST, Tamilarasi V, Alexander S. Effect of Double filtration plasmapheresis on various plasma components and patient safety– A prospective observational cohort study. Indian Journal of Nephrology. 2017; 27(5):377-383.

4. Kakde ST, Alexander S, David VG, Jacob S, Mohapatra A, Valson AT, Basu G*, Jacob CK, Hephzibah Julie, Varughese S, Tamilarasi V. To Study the Relationship of Creatinine and Cystatin C based estimated Glomerular filtration rates with measured Glomerular filtration rate in healthy adults from South Asia. (manuscript accepted for publication in Indian Journal of Nephrology).

5. Mohapatra A, Kakde S, Annapandian VM, Valson AT, Duhli N, Korula A, Matthai SM, Pulimood AB, David VG, Alexander S, Jacob S, Varughese S, Gopal B, Veerasamy T, John GT. Spectrum of biopsy proven renal disease in South Asian children: Two decades at a tropical tertiary care centre. Nephrology (Carlton). 2017 Aug 28 doi: 10.1111/nep.13160.

6. Vig T, Bindra MS, Kumar RM, Alexander S. Gastric Glomus Tumour Misdiagnosed as Gastric Carcinoid: An Unfamiliar Entity with Aids to Diagnosis and Review of Literature. J Clin Diagn Res. 2017 May;11(5):ED32-ED33. doi: 10.7860/JCDR/2017/27968.9912. Epub 2017 May 1.

7. Dutta AK, Paulose BK, Danda S, Alexander S, Tamilarasi V, Omprakash S. Recurrent truncating mutations in alanine-glyoxylate aminotransferase gene in two South Indian families with primary hyperoxaluria type 1 causing later onset end-stage kidney disease. Indian J Nephrol. 2016;26(4):288-90.

8. George N, Alexander S, David VG, Basu G, Mohapatra A, Valson AT, Jacob S, Pathak HR, Devasia A, Tamilarasi V, Varughese S. Comparison of Early Mechanical and Infective Complications in First Time Blind, Bedside, Midline Percutaneous Tenckhoff Catheter Insertion with Ultra Short Break-in Period in Diabetics and Non-Diabetics: Setting New Standards. Perit Dial Int. 2016 Apr 4. pii: pdi.2015.00097.

9. Margabandu S, Alexander S, Matthai SM, Korula A, Varughese S, Tamilarasi V. IgG4-related tubulointerstitial nephritis associated with interstitial pulmonary disease: Indian Journal of Nephrology. 2015; 25(2):113. DOI:10.4103/0971-4065.136886.

10. Radhakrishnan RC, Basu G, Varughese S, Mahopatra A, Valson AT, Alexander S, Jacob S, Pathak HR, Zaccharia U, Abraham P, Tamilarasi V. Impact of hepatitis B and C infections in renal transplantation. Indian Journal of Nephrology. 2014; 8(4). DOI:10.1016/j.ijt.2014.12.022.

11. David VG, Yadav B, Jeyaseelan L, Deborah MN, Jacob S, Alexander S, Varughese S, John GT. Prospective blood pressure measurement in renal transplant recipients. Indian Journal of Nephrology. 2014; 24(3):154-160.

12. Alexander S, Simon E, Burad D, Varughese S, David VG, Sudhakar G, Tamilarasi V, Jacob CK, Pusey CD. Esophageal Vasculitis in Granulomatosis with Polyangiitis.Tropical Gastroenterology. 2015 Apr-Jun;36(2):132-4.

13. Valson AT, Sundaram M, David VG, Deborah MN, Varughese S, Basu G, Mohapatra A,  Alexander SJose J, Roshan J, Simon B, Rebekah G, Tamilarasi V, Jacob CK. Profile of incident chronic kidney disease related-mineral bone disorders in chronic kidney disease Stage 4 and 5: A hospital based cross-sectional survey.Indian Journal of Nephrology. 2014; 24(2):97-107.

14. Alexander S, Fleming DH, Mathew BS, Varughese S, Jeyaseelan V, Tamilarasi V, Jacob CK, John GT. Pharmacokinetics of Concentration Controlled MycophenolateMofetil in Proliferative Lupus Nephritis- an Observational Cohort Study. Ther Drug Monit. 2014 Aug;36(4):423-32. doi: 10.1097/FTD.0000000000000031.

15. George P, Alexander S, Varughese S, Chacko BR, David VG, Gowrugari V, Tamilarasi V, Jacob CK. First Case on Successful Management of Manganism with Renal Transplantation. Transplantation. 2013;95(9):e58-e59.

16. Alexander S, David VG, Varughese S, Tamilarasi V, Jacob CK. A Case of Posterior reversible encephalopathy syndrome in a renal allograft recipient: A complication of immunosuppression? Indian Journal of Nephrology. 2013;23(2):137-139.

17. Alexander S, Raj P, Varughese S, David V, Tamilarasi V, Jacob CK.  Medical Image- Medical image. Disseminated infection with Nocardia asteroides. The New Zealand medical journal.2013;6:126.

18. Alexander S, Varughese S, David VG, Kodgire SV, Mukha RP, Kekre NS, Tamilarasi V, Jacob CK, John GT. Extensive emphysematous pyelonephritis in a renal allograft treated conservatively: case report and review of the literature. Transpl Infect Dis. 2012 Dec;14(6):E150-5. doi: 10.1111/tid.12016. Epub 2012 Oct 1.

19. Alexander S, Varughese S, George PJ, Kirubakaran R. Fenoldopam for preventing and treating acute kidney injury (Protocol). Cochrane Database of Systematic Reviews 2012, Issue 5. Art. No.: CD009838. DOI: 10.1002/14651858.CD009838.

20. Varughese S, Sundaram M, David VG, Basu G, Mohapatra A, Alexander S, Tamilarasi V. Letter to the Editor: Percutaneous PD catheter insertion after past abdominal surgeries. Indian Journal of Nephrology. 2012;22(3):230-231.

21. Varughese S, Sundaram M, Basu G, David VG, Mohapatra A, Alexander S, Tamilarasi V. Automated Peritoneal Dialysis in a patient with CKD 5 and Hansen’s disease – a case report. Indian Journal of Peritoneal Dialysis. 2010;19:30-31.

22. Varughese S, John GT, Alexander S, Deborah M.N, Neelakantan N, Ahamed.I, Tamilarasi V, Jacob CK. Pre-tertiary hospital care of patients with chronic kidney disease in India. Indian J Med Res.2007;126:28-33.

23. Jacob J, Alexander S, Thomas N. A fragile adolescent. New Zealand Medical Journal. 2006;119:1237.

24. Alexander S, John GT, Jesudason M, Jacob CK. Infections with atypical mycobacteria in renal transplant recipients. Indian J PatholMicrobiol 2007;50 (3): 482-484.

Awards

1. Fellow of the American Society of Nephrology (FASN), awarded by the 2017 American Society of Nephrology council.

2. 2nd prize for poster titled 'Why is IgA nephropathy aggressive in Indians? The GRACE IgANI Study: Epidemiology at Diagnosis and Follow-up' on Annual Research Day 2016 under the 'Super-specialty Category' held in CMC, Vellore.

3. The ISN-ANIO Clinical Nephropathology Certificate Program (CNC) was attended from March 1st 2014 to January 31st 2015 and Certificate of Completion was awarded by The International Society of Nephrology. 

4. Junior Medical Faculty Training Fellowship 2012-13 awarded by Christian Medical College, Vellore to undertake clinical and research training in Imperial College, London, UK for a period of three months (April 1st to June 30th, 2013).

5. Certification of completion of the educational activity titled “Updates on Transplantation” provided by American Academy of Continuing Medical Education.

6. B Braun Medical Trust Foundation Award 2008 for outstanding achievement in post-graduate studies in the field of Nephrology, awarded at the Annual B Braun Medical Trust Foundation Award Ceremony and Alumni Meet held at Chennai, 2008.

7. Best Paper Award and Gold medal for the Paper “Exposure controlled lupus nephritis in Class III and Class IV lupus nephritis” at the National Conference of the Indian Society of Nephrology held on the 17th- 19th Oct, 2008 at Pune, Maharashtra.

8. First prize in Endocrinology Winter Symposium Quiz held in CMC Vellore in 2006.

Abstracts/posters in conferences:

 

TH-PO093American Society of Nephrology, New Orleans, 2nd-5thth November 2017.  The GRACE IgA Nephropathy in Indians (GRACE-IgANI) Study: Epidemiology at Diagnosis and Follow-up. Alexander S, Franklin R, Korula A, Mathai SM, Jeyaseelan V, Theophilus V, Kang G, Tamilarasi V, David VG, Mohapatra A, Valson AT, Jacob S, Kakde ST, Ponnusamy B, Pusey C, Cook T, Daha MR, Seelan M, Baratt J, Feehally J, Varughese S, John GT. Department of Nephrology, Christian Medical College, Vellore, India.

Poster number 44- 3rd International Renal Pathology Conference, Delhi, 10th- 12th February 2016. The GRACE IgA Nephropathy in Indians (IGANI) Study: Epidemiology at Diagnosis and Follow-up. Alexander S, Franklin R, Korula A, Jeyaseelan V, Theophilus V, Kang G, Tamilarasi V, David VG, Mohapatra A, Valson AT, Jacob S, Kakde ST, Ponnusamy B, Mathai SM, Pusey C, Cook T, Daha MR, Seelen M, Barratt J, Feehally J, Varughese S, John GT. Department of Nephrology, Christian Medical College, Vellore, India.

PO41- 14th International Symposium on IgA Nephropathy, Tours, 15th- 17th September 2016. Why is IgA Nephropathy Aggressive in Indians? The GRACE IgANI Study: Epidemiology at Diagnosis. Alexander S, Franklin R, Korula A, Mathai SM, Jeyaseelan V, Theophilus V, Kang G, Tamilarasi V, David VG, Mohapatra A, Valson AT, Jacob S, Kakde ST, Ponnusamy B, Pusey C, Cook T, Daha MR, Seelan M, Baratt J, Feehally J, Varughese S, John GT. Department of Nephrology, Christian Medical College, Vellore, India.

TH-PO994- American Society of Nephrology, San Diego, 5th-8th November 2015. Early Mechanical and Infective Complications in First Time Blind, Bedside, Midline Percutaneous Tenckhoff Catheter Insertion with Ultra Short Break-in Perios: Setting New Standards. Alexander S, George NG, Varughese S. Department of Nephrology, Christian Medical College, Vellore, India.

SA-PO706- American Society of Nephrology, Atlanta, 7th-10th November 2013.The Achilles Heel of Lupus Nephritis Treatment- Identifying Non Adherence Using Hydroxychloroquine Blood Levels. Alexander S, Chusney G, Chusney VD, Lee J, Cairns T and Lightstone L. Department of Renal Medicine and Leslie Brent Laboratory, Imperial College Kidney and Transplant Institute, London, United Kingdom.

Poster Presentation- at the 32nd Annual Conference of the Indian Society of Nephrology Southern Chapter, 3rd-5th of February 2012, Chennai, India. Single Centre study on Theraputic Plasma Exchange for Renal Indications. Vasanth, Basu G, Mohapatra A, David VG, Alexander S, ValsanA,Tamilarasi V, Jacob CK

Podium paper presentation-at the 32nd Annual Conference of the Indian Society of Nephrology Southern Chapter, 3rd-5th of February 2012, Chennai, India. Acute Kidney Injury in Hematopoetic Stem Cell Transplant recipients. Venumadhavan, Basu G, Mohapatra A, David VG, Alexander S, ValsanA,Tamilarasi V, Jacob CK

Podium paper presentation- at the 32nd Annual Conference of the Indian Society of Nephrology Southern Chapter, 3rd-5th of February 2012, Chennai, India. BK Viraemia in Renal Allograft Recipient. Saravanan M, Basu G, Mohapatra A, David VG, Alexander S, ValsanA,Tamilarasi V, Jacob CK

Podium paper presentation- at the 32nd Annual Conference of the Indian Society of Nephrology Southern Chapter, 3rd-5th Feb 2012, Chennai, India. Acute Kidney Injury in critically ill patients: Prediction of mortality by AKIN criteria and APACHE. George N, Basu G, Mohapatra A, David VG, Alexander S, ValsanA,Tamilarasi V, Jacob CK

Poster presentation- at World Congress of Nephrology April 8-12, 2011 Vancouver, Canada. Prospective Assessment of Ambulatory Blood Pressure Measurement VS Office Blood Pressure Measurement in Renal Transplantation. David VG, Varughese S, Samuel G, Jeyseelan L, Mercy ND, Alexander S, Mohapatra A, Basu G, Sundaram M, Tamilarasi V, Jacob CK, John GT.

Abstract [SA 156]- Evaluation of Exposure- Controlled Mycophenolate (MPA) as Induction and Maintenance Therapy in Class III and IV incident Lupus Nephritis in a Tertiary Care Hospital in India- Alexander S, Sheikh NP,  Varughese S, Basu G, Sundaram M, David VG, Mohapatra A,  Mathew B,  Tamilarasi V, Jacob CK, John GT- accepted in WCN, held in Vancouver, Canada April 2011.

Poster presentation- at the 32nd Annual Conference of the Indian Society of Nephrology Southern Chapter, 11-13th, Feb 2011, Thrissur.  Role of Quantiferon TB in Hemodialysis Patients. Jacob S , Varughese S, David VG, Alexander S, Basu G, Mohapatra A, Tamilarasi V, Jacob CK

Podium paper presentation- at the 32nd Annual Conference of the Indian Society of Nephrology Southern Chapter, 11-13th, Feb 2011, Thrissur, India. Postransplant Glomerular Nephritis. Anand K , Varughese S, David VG, Alexander S, Basu G, Mohapatra A, Tamilarasi V, Jacob CK.

Podium paper presentation- at the 32nd Annual Conference of the Indian Society of Nephrology Southern Chapter, 11-13th, Feb 2011, Thrissur, India. Postransplant Diabetes Mellitus. Sachin KV, Varughese S Basu G,  Mohapatra A, David VG, Alexander S, ValsanA,Tamilarasi V, Jacob CK.

Podium paperpresentation- at the 31st Annual Conference of the Indian Society of Nephrology Southern Chapter, 11-13th, Feb 2011, Thrissur, India. Prospective Assessment of Ambulatory Blood Pressure Measurement VS Office Blood Pressure Measurement in Renal Transplantation. David VG, Varughese S, Samuel G, Jeyseelan L, Mercy ND, Alexander S, Mohapatra A, Basu G, Sundaram M, Tamilarasi V, Jacob CK, John GT.

Poster presentation – Varughese S, John G.T, Alexander S, Nithya N, Deborah MN, Tamilarasi V, Jacob C.K  “Evaluation of patients with Chronic Kidney Disease Stage 5 – a prospective analysis” at the Asian Pacific Congress of Nephrology, held at Seoul, South Korea in June 2010.

Poster presentation-  at the 30th Annual Conference of the Indian Society of Nephrology Southern Chapter, 4-6, Feb 2010, Pondicherry, India. Membranous Lupus Nephritis - A Single Centre Experience. Joseph J, Basu G, Varughese S, David VG, Mohapatra A, Alexander S, Korula A, Tamilarasi V, John GT, Jacob CK.

Podium paper presentation – Alexander S, Naseema S, Varughese S, Basu G, Tamilarasi V, Jacob C K, John GT. “A cohort study of exposure controlled Mycophenolic Acid in Class III and Class IV lupus nephritis.” at the Annual National Conference of the Indian Society of Nephrology held at Pune in December 2008. - Won the Best Paper Awardand Gold medal.

Poster presentation – Varughese S, John G.T, Alexander S, Deborah M.N, Kirubakaran M.G, Basilea V, Nithya N, Ahamed I, Dharan K.S, Suri A.D, Tamilarasi V, Jacob C.K  “Evaluation of patients with Chronic Kidney Disease Stage 5 – a prospective analysis” at the Annual National Conference of the Indian Society of Nephrology held at Cochin in December 2005.

Podium paper presentation – Varughese S, John G.T, Alexander S, Deborah M.N, Kirubakaran M.G, Basilea V, Nithya N, Balakrishnan N, Krishnamurthy K, Iqbal M, Jacob C.K “Evaluation of patients with Chronic Kidney Disease Stage 5 – a prospective analysis” at the Annual Conference of Southern Chapter of the Indian Society of Nephrology held at Chennai in February 2005. – Won theBest Paper Award and Gold medal.

Book publication

1.     Alexander S (2011). Lupus nephritis- advances in treatment. In Dakshinamurty KV, Raju TR, Deshpande P (Eds.), Postgraduate nephrology 2011 (pp.75-85). Hyderabad: Baxter India Pvt. Ltd.

2.     Jacob CK, Alexander S (2014). In Visweswaran KR (Ed.), Prescribing drugs in renal diseases 2014 (pp.44-54). Mumbai: True Life Media.

3.     Varughese S, Alexander S (2016). Nephropathy. In Thomas N, Kapoor N, Velavan J, Vasan S (Eds.), A practical guide to diabetes mellitus 2016 (pp.259-78). New Delhi: Jaypee Brothers Medical Publishers Pvt. Ltd.