Publications and Presentations

PUBLICATIONS

 

Original Research Manuscripts, *corresponding

 

1.     GBD 2015 SDG Collaborators. Measuring the health-related Sustainable Development Goals in 188 countries: a baseline analysis from the Global Burden of Disease Study 2015. The Lancet. 2016 Oct 8;388(10053):1813-1850.

2.     GBD 2015 Mortality and Causes of Death Collaborators. Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980-2015: a systematic analysis for the Global Burden of Disease Study 2015. The Lancet. 2016 Oct 8;388(10053):1459-1544.

3.     GBD 2015 Risk Factors Collaborators. Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015. Lancet. 2016 Oct 8;388(10053):1659-1724.

4.     Tavpritesh Sethi, Anurag Agrawal, Aditya Nagori, Suveen Angraal, Sundeep Salvi. Graphical Modeling Driven Policy Insights for Household Air Pollution: Insights from 204,912 Patients’ POSEIDON Study. Proceedings of the 2nd Indian Workshop on Machine Learning, IIT Kanpur 2016 (https://www2.cse.iitk.ac.in/~iwml/2016/papers/iWML_2016_paper_inv.pdf)

5.     Anchal Sharma, Asgar Hussain Ansari, Renu Kumari, Rajesh Pandey, Rakhshinda Rehman, Bharati Mehani, Binuja Varma, Bapu K Desiraju, Ulaganathan Mabalirajan, Anurag Agrawal, Arijit Mukhopadhyay. Human brain harbors single nucleotide somatic variations in functionally relevant genes possibly mediated by oxidative stress. F1000 research Oct 2016 5:2520

6.     Singh S, Bodas M, Bhatraju NK, Pattnaik B, Gheware A, Parameswaran PK, Thompson M, Freeman M, Mabalirajan U, Gosens R, Pabelick C, Linneberg A, Prakash YS, Agrawal A*. Hyperinsulinemia adversely affects lung structure and function. Am J Physiol Lung Cell Mol Physiol. 2016 May 1;310(9):L837-45.

7.     Pattnaik B, Bodas M, Bhatraju NK, Ahmad T, Pant R, Guleria R, Ghosh B, Agrawal A*. IL-4 promotes asymmetric dimethylarginine accumulation, oxo-nitrative stress, and hypoxic response-induced mitochondrial loss in airway epithelial cells. J Allergy Clin Immunol. 2016 Feb 23. pii: S0091-6749(16)00108-1.

8.     Soree P, Gupta RK, Singh K, Desiraju K, Agrawal A, Vats P, Bharadwaj A, Baburaj TP, Chaudhary P, Singh VK, Verma S, Bajaj AC, Singh SB. Raised HIF1α during normoxia in high altitude pulmonary edema susceptible non-mountaineers. Sci Rep. 2016 May 23;6:26468.

9.     Gupta RK, Himashree G, Singh K, Soree P, Desiraju K, Agrawal A, Ghosh D, Dass D, Reddy PK, Panjwani U, et al. Elevated pulmonary artery pressure and brain natriuretic peptide in high altitude pulmonary edema susceptible non-mountaineers. Sci Rep. 2016 Feb

10.  Abhimanyu, Bose M, Varma-Basil M, Jain A, Sethi T, Tiwari PK, Agrawal A, Banavaliker JN, Bhowmick KT. Establishment of Elevated Serum Levels of IL-10, IL-8 and TNF-β as Potential Peripheral Blood Biomarkers in Tubercular Lymphadenitis: A Prospective Observational Cohort Study. PLoS One. 2016 Jan 19;11(1):e0145576.

11.  Salvi S, Apte K, Madas S, Barne M, Chhowala S, Aggarwal K, Sethi T, Agrawal A, Gogtay J. What ails India? A one-day point prevalence study of symptoms and medical conditions in 204,912 patients visiting primary healthcare practitioners across 880 cities and towns in India. Results of the POSEIDON Study. Lancet Global Health. 2015 Dec 3 (12) e776–e784

12.  Negi V, Paul D, Das S, Bajpai P, Singh S, Mukhopadhyay A, Agrawal A, Ghosh B.  Altered expression and editing of miRNA-100 regulates iTreg differentiation. Nucleic Acids Res. 2015 Jul 23. pii: gkv752.

13.  Singh VP, Aggarwal R, Singh S, Banik A, Ahmad T, Patnaik BR, Nappanveettil G, Singh KP, Aggarwal ML, Ghosh B, Agrawal A. Metabolic Syndrome Is Associated with Increased Oxo-Nitrative Stress and Asthma-Like Changes in Lungs. PLoS One. 2015 Jun 22;10(6):e0129850.

14.  Aggarwal S, Gheware A, Agrawal A, Ghosh S, Prasher B, Mukerji M; Indian Genome Variation Consortium. Combined genetic effects of EGLN1 and VWF modulate thrombotic outcome in hypoxia revealed by Ayurgenomics approach. J Transl Med. 2015 Jun 6;13:184.

15.  Kumar A, Das S, Agrawal A, Mukhopadhyay I, Ghosh B. Genetic association of key Th1/Th2 pathway candidate genes, IRF2, IL6, IFNGR2, STAT4 and IL4RA, with atopic asthma in the Indian population. J Hum Genet. 2015 Aug;60(8):443-8.

16.  Ahmad T, Mukherjee S, Pattnaik B, Kumar M, Singh S, Kumar M, Rehman R, Tiwari BK, Jha KA, Barhanpurkar AP, Wani MR, Roy SS, Mabalirajan U, Ghosh B, Agrawal A*. Miro1 regulates intercellular mitochondrial transport & enhances mesenchymal stem cell rescue efficacy. EMBO J. 2014; 33 (9), 994-1010

17.  Makhija L, Krishnan V, Rehman R, Chakraborty S, Maity S, Mabalirajan U, Chakraborty K, Ghosh B, Agrawal A*. Chemical Chaperones Mitigate Experimental Asthma by Attenuating Endoplasmic Reticulum Stress. Am J Respir Cell Mol Biol. 2013 Dec 3. [Epub ahead of print]

18.  Das S, Kumar M, Negi V, Pattnaik B, Prakash YS, Agrawal A, Ghosh B. MicroRNA-326 Regulates Pro-Fibrotic Functions of Transforming Growth Factor-β in Pulmonary Fibrosis. Am J Respir Cell Mol Biol. 2013 Nov 26. [Epub ahead of print]

19.  Raj D, Lodha R, Mukherjee A, Sethi T, Agrawal A, Kabra SK. Fractional Exhaled Nitric Oxide (FENO) in Children with Acute Exacerbation of Asthma. Indian Pediatr. 2013 Sep 5. [Epub ahead of print]

20.  Sussan TE, Ingole V, Kim JH, McCormick S, Negherbon J, Fallica J, Akulian J, Yarmus L, Feller-Kopman D, Wills-Karp M, Horton MR, Breysse PN, Agrawal A, Juvekar S, Salvi S*, Biswal S*. Source of Biomass Cooking Fuel Determines Pulmonary Response to Household Air Pollution. Am J Respir Cell Mol Biol. 2013 Oct 8. [Epub ahead of print]

21.  Mehla K, Balwani S, Agrawal A, Ghosh B*. Ethyl gallate attenuates acute lung injury through Nrf2 signaling. Biochimie. 2013 Dec;95(12):2404-14.

22.  Raj D, Lodha R, Pandey A, Mukherjee A, Agrawal A, Kabra SK; New Delhi Childhood Asthma Study Group. Aeroallergen sensitization in childhood asthmatics  in northern India. Indian Pediatr. 2013 Dec 8;50(12):1113-8..

23.  Adlakha YK, Khanna S, Singh R, Singh VP, Agrawal A, Saini N*. Pro-apoptotic miRNA-128-2 modulates ABCA1, ABCG1 and RXRα expression and cholesterol homeostasis. Cell Death Dis. 2013 Aug 29;4:e780.

24.  Agrawal A*, Bhattacharya J, Baranwal N, Bhatla S, Dube S, Sardana V, Gaur DR, Balazova D, Brahmachari SK. Integrating health care delivery and data collection in rural India using a rapidly deployable ehealth center. PLoS Med. 2013;10(6):e1001468. doi: 10.1371/journal.pmed.1001468.

25.  Sinha A, Yadav AK, Chakraborty S, Kabra SK, Lodha R, Kumar M, Kulshreshtha A, Sethi T, Pandey R, Malik G, Laddha S, Mukhopadhyay A, Dash D, Ghosh B, Agrawal A*. Exosome-enclosed microRNAs in exhaled breath hold potential for biomarker discovery in patients with pulmonary diseases. J Allergy Clin Immunol. 2013 Jul;132(1):219-22.

26.   Mabalirajan U*, Ahmad T, Rehman R, Leishangthem GD, Dinda AK, Agrawal A, Ghosh B, Sharma SK. Baicalein reduces airway injury in allergen and IL-13 induced airway inflammation. PLoS One. 2013 Apr 30;8(4):e62916.

27.  Laddha SV, Nayak S, Paul D, Reddy R, Sharma C, Jha P, Hariharan M, Agrawal A, Chowdhury S, Sarkar C, Mukhopadhyay A*. Genome-wide analysis reveals downregulation of miR-379/miR-656 cluster in human cancers. Biol Direct. 2013 Apr 24;8:10.

28.  Mabalirajan U, Rehman R, Ahmad T, Kumar S, Singh S, Leishangthem GD, Aich J, Kumar M, Khanna K, Singh VP, Dinda AK, Biswal S, Agrawal A, Ghosh B*. Linoleic acid metabolite drives severe asthma by causing airway epithelial injury. Sci Rep. 2013;3:1349.

29.  Kulshreshtha A, Ahmad T, Agrawal A, Ghosh B*. Proinflammatory role of epithelial cell-derived exosomes in allergic airway inflammation. J Allergy Clin Immunol. 2013 Apr;131(4):1194-203, 1203.e1-14.

30.  Ahmad T, Aggarwal K, Pattnaik B, Mukherjee S, Sethi T, Tiwari BK, Kumar M, Micheal A, Mabalirajan U, Ghosh B, Sinha Roy S, Agrawal A*. Computational classification of mitochondrial shapes reflects stress and redox state. Cell Death Dis. 2013 Jan 17;4:e461.

31.  Aich J, Mabalirajan U, Ahmad T, Khanna K, Rehman R, Agrawal A, Ghosh B*. Resveratrol attenuates experimental allergic asthma in mice by restoring inositol polyphosphate 4 phosphatase (INPP4A). Int Immunopharmacol. 2012 Dec;14(4):438-43.

32.  Kumar A, Sharma S, Agrawal A, Ghosh B*. Association of the -1072G/A polymorphism in the LTC4S gene with asthma in an Indian population. Int Arch Allergy Immunol. 2012;159(3):271-7. doi: 10.1159/000336675. Epub 2012 Jun 21.

33.  Sharma A, Kumar M, Ahmad T, Mabalirajan U, Aich J, Agrawal A, Ghosh B*. Antagonism of mmu-mir-106a attenuates asthma features in allergic murine model. J Appl Physiol (1985). 2012 Aug;113(3):459-64.

34.  Sinha A, Krishnan V, Sethi T, Roy S, Ghosh B, Lodha R, Kabra S, Agrawal A*. Metabolomic signatures in NMR Spectra of Exhaled Breath Condensate identify asthma. Eur Resp J  2012 Feb 39(2)

35.  Kumar M, Ahmad, T, Sharma A, Mabalirajan U, Kulshreshtha A, Agrawal A, Ghosh B*. Let-7 microRNA-mediated regulation of IL-13 and allergic airway inflammation. J Allergy Clin Immunol 2011. 128(5):1077-1085.

36.  Aggarwal S, Pandey R, Pasha QA, Agrawal A, Ghosh S, Prasher B*, Mukerji M*. EGLN1 involvement in high altitude adaptation: a lead from genetic analysis of extreme constitutions types in Ayurveda. Proceedings National Academy of Sciences (USA) 2010. 107 (44), 18961-6

37.  Ahmad T, Mabalirajan U, Aich J, Makhija L, Ghosh B, Agrawal A*. Simvastatin Improves Epithelial Dysfunction and Airway Hyperresponsiveness: From ADMA to Asthma. Am J Resp Cell Mol Biol 2011. 44(4):531-9

38.  Ahmad T, Mabalirajan U, Hasija K, Ghosh B, Agrawal A*. Mepacrine treatment attenuates allergic airway remodeling segregated from airway inflammation in mice. Int Immunopharmacol 2011, 11 (1), 74-8

39.  Agrawal A*, Agrawal A, Pandit M, Kalyanpur A., Systematic survey of discrepancy rates in an international teleradiology service. Emerg Radiol 2011, 18 (1), 23-9

40.  Mabalirajan U, Ahmad T, Leishangthem GD, Dinda AK, Agrawal A, Ghosh B*. L-arginine reduces mitochondrial dysfunction and airway injury in murine allergic airway inflammation. Int Immunopharmacol. 2010 Dec;10(12):1514-9

41.  Mabalirajan U, Ahmad T, Leishangthem GD, Duraisamy AJ, Dinda AK, Agrawal A, Ghosh B*. Beneficial effects of high dose of L-Arginine on airway hyperresponsiveness and airway inflammation in a murine model of asthma. J Allergy Clin Immunol 2010 Mar;125(3):626-35.

42.  Ahmad T, Mabalirajan U, Ghosh B, and Agrawal A*.  Altered Asymmetric Dimethyl Arginine metabolism in allergically inflamed mice lungs. Am J Resp Cell Mol Biol 2010 Jan;42(1):3-8

43.  Agrawal A*, Sinha A, Ahmad T, Singh P, Sharma A, Ghosh B. Maladaptation Of Critical Cellular Functions In Asthma: A Bioinformatic Analysis. Physiol Genomics 2009 Dec; 40(1):1-7

44.  Mabalirajan U, Aich J, Agrawal A, Ghosh B. Mepacrine inhibits sub-epithelial fibrosis by reducing the expression of arginase and TGF-{beta}1 in an extended sub-acute mouse model of allergic asthma. Am J Physiol Lung Cell Mol Physiol 2009, June 19.

45.  Singh S, Taneja B, Salvi S, Agrawal A*. Physical properties of intact proteins may predict allergenicity or lack thereof. PLoS One 2009, May 27

46.  Ahmad T, Mabalirajan U, Joseph DA, Makhija L, Singh VP, Ghosh B, Agrawal A*. Exhaled nitric oxide estimation by a simple and efficient non – invasive technique and its utility as a marker of airway inflammation in mice. J Appl Physiol 2009, Apr 30

47.  Sharma A, Aich J, Kumar M, Hariharan M, Brahmachari S, Agrawal A, Ghosh B*. Post-Transcriptional Regulation of Interleukin-10 Expression by hsa-miR-106a, Proc Nat Acad Sci (USA) 2009, Feb

48.  Agrawal A*, Singh SK, Singh VP, Murphy E, Parikh I. A novel method to partition nasal and pulmonary resistance changes during non-invasive plethysmography in mice. J Appl Physiology  2008, 105: 1975–79

49.  Agrawal A*, Rengarajan S, Fahim M, Adler K, Ghosh B, Dickey BF. Inhibition of mucin secretion with MARCKS related peptide improves airway obstruction in a mouse model of asthma. J Appl Physiol. 2007,102(1):399-405

50.  Nigam R, Sansores L, Sepulveda G, Tuvim M, Adachi R, Dickey BF, Agrawal A*. Expression and transcriptional regulation of Munc18 isoforms in mast cells. Biochim Biophys Acta. 2005, 1728(1-2):77-83

51.  Agrawal A*, Agrawal KP, Chhabra SK, Khanduja A, Gangul SV, Mehta D. Increased intracellular sodium in airway hyperreactivity and asthma: quantitative aspects and causative mechanisma. Lung 2005, 183(3): 375-387

52.  Agrawal A*, Adachi R, Tuvim MJ, Yan XT, Teich AH, Dickey BF. Gene structure and promoter function of Munc18-2, an exocytic Sec1 related protein. Biochem Biophys Res Comm 2000, 276(3): 817-22.

53.  Agrawal A and Agrawal KP. Body Plethysmographic measurement of thoracic gas volume without panting against a shutter. J Appl Physiol 1996, 81(2): 1007-11.

 

Reviews

54.  K Desiraju and A Agrawal*. Impulse Oscilometry: The state of art for lung function testing. Lung India 2016

55.  A Agrawal* and U Mabalirajan. Rejuvenating Cellular Respiration for Optimizing Respiratory Function – Targeting Mitochondria. Am J Physiol Lung Cell Mol Physiol 2016

56.  A Agrawal*, YS Prakash. Obesity, Metabolic Syndrome, and Airway Disease: A Bioenergetic Problem? Immunology and Allergy Clinics of North America 2014; 34 (4), 785-796                      

57.  A Agrawal*. Urban, obese, allergic, and breathless: the shape of things to come?  Immunology and Allergy Clinics of North America 2014; 34 (4), xiii-xviii

58.  Singh S, Prakash YS, Linneberg A, Agrawal A*. Insulin and the Lung: Connecting Asthma and Metabolic Syndrome. J Allergy. 2013;2013:627384.

59.  Agrawal A*, Agrawal A, Bansal V, Pandit M. A systematic approach to interpretation of heterogeneous lung attenuation on computed tomography of the chest. Lung India. 2013 Oct;30(4):327-334.

60.  Leishangthem GD, Mabalirajan U, Singh VP, Agrawal A, Ghosh B, Dinda AK*. Ultrastructural changes of airway in murine models of allergy and diet-induced metabolic syndrome. ISRN Allergy. 2013;2013:261297

61.  Agrawal A*, Ahmad T, Mabalirajan U, Ghosh B. Emerging interface between asthma and metabolic syndrome. Am J Resp Cell Mol Biol  2011. 44 (3):270-5

62.  Sethi T, Agrawal A*. Structure and function of the tuberculous lung: considerations for inhaled therapies. Tuberculosis (Edinb). 2011 Jan; 91(1):67-70

63.  Agrawal A*, Mahabalirajan U, Ram A and Ghosh B. Novel approaches for inhibition of mucus hypersecretion in asthma. Inflammation &  Allergy Drug Discovery 2007; 1:188-192 (Review)

64.  Agrawal A and Hanania N. Management of life threatening asthma: Diagnostic considerations. Journal of Critical Illness. 2005, 20(2): 44-48.

65.  Agrawal A and Hanania N. Difficult to treat asthma. Adv Studies Medicine 2004, 4(5): 235-242.

     

     Book Chapters

66.  Mukherjee S, Bhatraju N, Ahmad T, Agrawal A*, Regulation of Mitochondrial Transport by Mesenchymal Stem Cells,  in “The Biology and Therapeutic Application of Mesenchymal Cells" ed: Kerry Atkinson, Wiley Press 2015 (in press)

67.  Kumar A, Ghosh B, Agrawal A. Inherited factors in obstructive lung diseases in India. Genomics and Health in Developing World. Oxford University Press ed D. Kumar (2012)

68.  Tavpritesh Sethi and Anurag Agrawal*. Pulmonary function testing in COPD, in Textbook of Pulmonary and Critical Care Medicine. Editor S.K. Jindal.  Jaypee Press. 2011

69.  Agrawal A* and Agrawal A. Postprimary tuberculosis, in In emedicine.com: Radiology, Chest. Amorosa JK, Coombs BD, Newell JD, Krasny RM, Lin EC eds. WebMD Inc. USA, topic 412, 2007, update 2011. [Book Chapter]

70.  Agrawal A and Agrawal A. Nontuberculous mycobacterial infections, In emedicine.com: Radiology, Chest. Singh SP, Coombs BD, Stern EJ, Krasny Rm, White CS eds. WebMD Inc. USA, topic 413, 2005, update 2011. [Book Chapter]

71.  Evans C, Agrawal A, Dickey BF.  Novel strategies to reduce excessive airway mucus secretion, In: Lung Biology in Health and Disease: Therapeutic Targets of Airway Inflammation. NT Eissa and DP Huston, eds. Marcel-Dekker, Inc. New York, 177:495-518, 2003.

72.   Agrawal A, Hanania N. Inhaled corticosteroids as monotherapy for asthma, in Harrison’s Textbook of Medicine 16th edition, Chapter 236. Asthma, online update, Nov. 2002.

73.  Agrawal KP and Agrawal A. Body Plethysmography, in Conference Syllabus & PFT Manual, Agrawal KP, Hyatt RE eds. International symposium on pulmonary function testing, VP Chest Institute, University of Delhi 1995.

 

Editorials, Commentaries and Opinions

74.  Singh S, Bodas M, Bhatraju NK, Pattnaik B, Gheware A, Parameswaran PK, Thompson M, Freeman M, Mabalirajan U, Gosens R, Ghosh B, Pabelick C, Linneberg A, Prakash YS, Agrawal A. Author response to letter to editor: Hyperinsulinemia adversely affects lung structure and function. Am J Physiol Lung Cell Mol Physiol. 2016 Jul 1;311(1):L183-4

75.  Agrawal A. Childhood Obesity related Co-morbidities and Retinol Binding Protein 4: An Evolving Understanding. Indian J Pediatr. 2015 Sep;82(9):779-80.

76.  Agrawal A, Prakash YS, Linneberg A. Body mass index is not a stronger predictor than the metabolic syndrome for future asthma in women. Am J Respir Crit Care Med. 2014 Jan 15;189(2):231-2

77.  Agrawal A, Sood A, Linneberg A, Ghosh B. Mechanistic understanding of the effect of obesity on asthma and allergy. J Allergy. 2013;2013:598904.

78.  Salvi S, Agrawal A. India needs a national COPD prevention and control programme. J Assoc Physicians India. 2012 Feb;60 Suppl:5-7

79.  Agrawal A, Living in a Bayesian World: Scientific Deduction through Induction, Current Science 102(5):676-678, 2012

80.  Agrawal A and Sharma A. Likelihood of False-Positive Results in High-Impact Journals Publishing Groundbreaking Research. Infection and Immunity 2012

81.  U. Mabalirajan, Agrawal A, Ghosh B. 15-Lipoxygenase eicosanoids are the putative ligands for vanilloid receptors and peroxisome proliferator-activated receptors (PPARs). Proc Natl Acad Sci U S A. 109:E1 2012

82.  Agrawal A, The Faustian bargain in data driven discovery: Lessons from Medicine. Current Science 2011

83.  Kumar M, Mabalirajan U, Agrawal A, Ghosh B. Proinflammatory role of let-7 miRNAs in experimental asthma? J Biol Chem. 2010 Nov 26;285(48):le19

84.  Agrawal A. Molecular Th2 phenotypes of asthma: new biomarker or NO? Am J Respir Crit Care Med. 2010 Feb 15;181(4):419

85.  Mabalirajan U, Agrawal A, Ghosh B. Comment on "Ym1/2 promotes Th2 cytokine expression by inhibiting 12/15(S)-lipoxygenase: identification of a novel pathway for regulating allergic inflammation". J Immunol. 2009 Nov 15;183(10):6039

86.  Agrawal A. Genetics of Asthma: The Road Ahead. National Medical Journal of India 2009. 22(3):113-115

87.  Agrawal A. Mucous obstruction and airway hyperresponsiveness in mice. Am J Resp Crit Care Med 2008 (Letter to editor)

88.  Agrawal A. Bronchial thermoplasty in asthma. N Engl J Med 2007. 356(26) 2745-2746 (Letter to editor)

89.  Agrawal A* and Ram A. Commentary on Restrained whole body plethysmography for measure of strain-specific and allergen-induced airway responsiveness in conscious mice. J Appl Physiol. 2007 Jun;102(6):2411-12 (Letter to editor)

90. Agrawal A. Futile medical care: an ethical battleground. Natl Med J India. 2009 Jul-Aug;22(4):219-20.