Publications and Presentations

1. Penmatsa, A.*, Wang, K. H.* & Gouaux, E. X-ray structures of Drosophila dopamine transporter in complex with nisoxetine and reboxetine. Nat. Str. Mol. Biol. (2015). 22, 506-508. 

2. Wang, K. H.* Penmatsa, A.* & Gouaux, E. Neurotransmitter and psychostimulant recognition by the dopamine transporter. Nature. (2015). 521, 322-327. 

3. Whittaker, M. M., Penmatsa, A. & Whittaker, J. W. The Mtm1p carrier and pyridoxal 5'-phosphate cofactor trafficking in yeast mitochondria. Arch. Biochem. Biophys. (2015). 568, 64-70 

4. Penmatsa, A. & Gouaux, E. How LeuT shapes our understanding of the mechanisms of sodium-coupled neurotransmitter transporters. J. Physiol. (2014), 592, 863-869.

5. Wang, H., Goehring, A., Wang, K. H., Penmatsa, A., Ressler, R. & Gouaux, E. Structural basis for action by diverse antidepressants on biogenic amine transporters. Nature. (2013). 503, 141-145. 

6. Penmatsa, A.*, Wang, K. H.* & Gouaux, E. X-ray structure of dopamine transporter elucidates antidepressant mechanism. Nature. (2013). 503, 85-90. 

7. Rajanikanth, V., Srivastava, S. S., Singh, A. K. , Rajyalakshmi, M., Chandra, K., Aravind, P., Sankaranarayanan, R. & Sharma Y. Aggregation-prone near-native intermediate formation during unfolding of a structurally similar nonlenticular βγ-crystallin domain. Biochemistry. (2012), 51, 8502-8513. 

8. Aravind, P.*, Mishra, A.*, Suman, S. K.*, Jobby, M. K., Sankaranarayanan, R. & Sharma, Y. The βγ-Crystallin superfamily contains a universal motif for binding calcium. Biochemistry. (2009), 48, 12180–12190

9. Roy, S.*, Aravind, P.*, Madhurantakam, C., Ghosh, A. K., Sankaranarayanan, R. & Das, A. K. Crystal structure of a fungal protease inhibitor from Antheraea mylitta. J. Struct. Biol. (2009), 166, 79-87. 

10. Aravind, P., Suman, S. K., Mishra, A., Sharma, Y. & Sankaranarayanan, R. Three-dimensional domain swapping in nitrollin, a single-domain βγ-crystallin from Nitrosospira multiformis, controls protein conformation and stability but not dimerization. J. Mol. Biol. (2009), 385, 163-177. 

11. Aravind, P., Wistow, G., Sharma, Y. & Sankaranarayanan, R. Exploring the limits of sequence and structure in a variant βγ-crystallin domain of the protein absent in melanoma-1 (AIM1). J. Mol. Biol. (2008), 381, 509-518. 

12. Aravind, P., Chandra, K., Reddy, P. P., Jeromin, A., Chary, K. V. & Sharma, Y. Regulatory and Structural EF-hand motifs of Neuronal Calcium Sensor-1: Mg2+ modulates Ca2+-binding, Ca2+- Induced conformational changes, and Equilibrium unfolding transitions. J. Mol. Biol. (2008), 376, 1100-1115. 

13. Mikhaylova, M., Sharma, Y., Reissner, C., Nagel, F., Aravind, P., Rajini, B., Smalla K. H., Gundelfinger, E. D. & Kreutz, M. R. Neuronal Ca2+ signaling via caldendrin and calneurons. Biochim. Biophys. Acta. (2006), 1763, 1229-1237. 

14. Roy, S.*, Aravind, P*., Madhurantakam, C., Ghosh, A. K., Sankaranarayanan, R. & Das, A. K. Crystallization and preliminary X-ray diffraction analysis of a protease inhibitor from the haemolymph of the Indian tasar silkworm Antheraea mylitta. Acta. Cryst. Sect. F. (2006), 62, 669-671. 

15. Aravind, P., Rajini, B., Sharma, Y. & Sankaranarayanan, R. Crystallization and preliminary X-ray crystallographic investigations on a βγ-crystallin domain of absent in melanoma 1 (AIM1), a protein from Homo sapiens. Acta. Cryst. Sect. F. (2006), 62, 282-284. 

*equal contribution