Publications and Presentations

1. Li W, Notani D, Rosenfeld MG. Enhancers as non-coding RNA transcription units: recent insights and future perspectives. Nat Rev Genet. 2016 Mar 7. doi: 10.1038/nrg.2016.4

2. Han Y, Rand KA, Hazelett DJ, Ingles SA, Kittles RA, Strom SS, Rybicki BA, Nemesure B, Isaacs WB, Stanford JL, Zheng W, Schumacher FR, Berndt SI, Wang Z, Xu J, Rohland N, Reich D, Tandon A, Pasaniuc B, Allen A, Quinque D, Mallick S, Notani D, Rosenfeld MG, Jayani RS, Kolb S, Gapstur SM, Stevens VL, Pettaway CA, Yeboah ED, Tettey Y, Biritwum RB, Adjei AA, Tay E, Truelove A, Niwa S, Chokkalingam AP, John EM, Murphy AB, Signorello LB, Carpten J, Leske MC, Wu SY, Hennis AJ, Neslund-Dudas C, Hsing AW, Chu L, Goodman PJ, Klein EA, Zheng SL, Witte JS, Casey G, Lubwama A, Pooler LC, Sheng X, Coetzee GA, Cook MB, Chanock SJ, Stram DO, Watya S, Blot WJ, Conti DV, Henderson BE, Haiman CA. Prostate Cancer Susceptibility in Men of African Ancestry at 8q24. J Natl Cancer Inst. 2016 Jan 27;108(7). doi: 10.1093/jnci/djv431

3. Telese F, Ma Q, Perez PM, Notani D, Oh S, Li W, Comoletti D, Ohgi KA, Taylor H, Rosenfeld MG. LRP8-Reelin-Regulated Neuronal Enhancer Signature Underlying Learning and Memory Formation. Neuron. 2015 May 6;86(3):696-710. doi: 10.1016/j. Neuron. 2015.03.033. Epub 2015 Apr 16.

4. Li W, Lam MT, Notani D. Enhancer RNAs. Cell Cycle. 2014;13(20):3151-2.doi: 10.4161/15384101.2014.962860.

5. Skowronska-Krawczyk D, Ma Q, Schwartz M, Scully K, Li W, Liu Z, Taylor H, Tollkuhn J, Ohgi KA, Notani D, Kohwi Y, Kohwi-Shigematsu T and Rosenfeld MG. Required enhancer-matrin-3 network interactions for a homeodomain transcription program. Nature. 2014 Aug 3. doi: 10.1038/nature1357.

6. Li W*, Notani D*, Ma Q, Tanasa B, Nunez E, Chen AY, Merkurjev D, Zhang J, Ohgi K, Song X, Oh S, Kim H-S, Glass CK, and Rosenfeld MG. Functional Importance of eRNAs for Estrogen-dependent Transcriptional Activation Events. Nature. 2013. 498(7455):516-20. (* These authors contributed equally to this work)

Comment In: Redmond AM, Carroll JS. Enhancer-derived RNAs: 'spicing up' transcription programs. EMBO J. 2013. 32(15):2096-8.

Research Highlight: Carlos A Melo, Nicolas Léveillé, and Reuven Agami. eRNAs reach the heart of transcription. Cell Research. 2013. doi: 10.1038/cr.2013.97.

Recommended by Faculty of 1000 Biology.

7. Dunkel Y, Ong A, Notani D, Mittal Y, Lam M, Mi X, Ghosh P. STAT3 protein up-regulates G?-interacting vesicle-associated protein (GIV)/Girdin expression, and GIV enhances STAT3 activation in a positive feedback loop during wound healing and tumor invasion/metastasis. J Biol Chem. 2012. 287(50):41667-83.

8. Notani D, Ramanujam PL, Kumar PP, Gottimukkala KP, Kumar-Sinha C, Galande S.N-terminal PDZ-like domain of chromatin organizer SATB1 contributes towards its function as transcription regulator. J Biosci. 2011. 36(3):461-9.

9. Harismendy O*, Notani D*, Song X, Rahim NG, Tanasa B, Heintzman N, Ren B, Fu XD, Topol EJ, Rosenfeld MG, Frazer KA. 9p21 DNA variants associated with coronary artery disease impair interferon-? signaling response. Nature. 2011. 470(7333):264-8. (* These authors contributed equally to this work)

Recommended by Faculty of 1000 Biology.

10. Lakshminarayana Reddy CN, Vyjayanti VN, Notani D, Galande S and Kotamraju S. Down-regulation of the global regulator SATB1 by statins in COLO205 colon cancer cells. Molecular Medicine Reports. 2010. 3(5)857-861.

11. Vempati RK, Jayani RS, Notani D, Sengupta A, Galande S, Haldar D. p300 mediated acetylation of histone H3 lysine 56 functions in DNA damage response in mammals. J Biol Chem. 2010. 285(37):28553-64.

12. Notani D, Limaye AS, Kumar PP, Galande S. Phosphorylation-Dependent regulation of SATB1, the higher-order chromatin organizer and global gene regulator. Methods Mol Biol. 2010. 647:317-35.

13. Ahlfors H, Limaye A, Elo LL, Tuomela S, Burute M, Gottimukkala K, Notani D, Rasool O, Galande S, Lahesmaa R. SATB1 dictates expression of multiple genes including IL-5 involved in human T helper cell differentiation. Blood. 2010.116(9):1443-53.

14. Notani D, Gottimukkala KP, Jayani RS, Limaye A, Damle MV, Mehta S, Purbey PK, Joseph J and Galande S. Global regulator SATB1 recruits ?-catenin and mediates Wnt/?-catenin response. PLoS Biol. 2010. 8(1):e1000296. Synopsis: Sedwick, C. SATB1 makes a splash in T cell Wnt signaling. PLoS Biol. 2010. e1000295. doi:10.1371/journal.pbio.1000295.

15. Purbey PK, Singh S, Notani D, Kumar PP, Limaye AS, Galande S. Acetylation-dependent interaction of SATB1 and CtBP1 mediates transcriptional repression by SATB1. Mol. Cell. Biol. 2009. 29:1321-37.

16. Galande S, Purbey PK, Notani D, and Kumar PP. The third dimension of gene regulation: Organization of dynamic chromatin loopscape by SATB1. Curr. Opin. Genet. Dev. 2007. 17: 408-417.

17. Kumar PP, Mehta S, Purbey PK, Notani D, Jayani RS, Purohit HJ, Raje DV, Ravi DS, Bhonde RR, Mitra D, and Galande S. SATB1-Binding Sequences and Alu-Like Motifs Define a Unique Chromatin Context in the Vicinity of Human Immunodeficiency Virus Type 1 Integration Sites. J Virol. 2007. 81:5617-5627.

18. Kumar PP, Bischof O, Purbey PK, Notani D, Urlaub U, Dejean A, and Galande S. Functional interaction between PML and SATB1 regulated chromatin loop architecture and transcription of the MHC class I locus. Nat. Cell Biol. 2007. 9: 45-56.

19. Kumar PP, Purbey PK, Sinha CK, Notani D, Limaye A, Jayani RS, and Galande S. Phosphorylation of SATB1, a global gene regulator, acts as a molecular switch regulating its transcriptional activity in vivo. Mol Cell. 2006. 22:231-243.