Publications and Presentations

Research articles

Ø  J.K. Manesia, M. Franch, D. Tabas-Madrid, R. Nogales-Cadenas, T. Vanwelden, E. Van Den Bosch, Z. Xu, S. Aerts, A. Pascual-Montano, S. Khurana, C.M. Verfaillie. Distinct Molecular Signature of Fetal Liver and Adult Hematopoietic stem cells Identifies Novel Regulators of Hematopoietic stem cells. Stem Cells and Development 2016. In press * As Co-corresponding author

Ø  S. Khurana*, S. Schouteden, JK Manesia. A Santamaria-Martínez, J Huelsken, A Lacy-Hulbert, C Verfaillie. Outside-in integrin signaling via Periostin- Integrin-αvβ3 regulates Hematopoietic stem cell quiescence. Nature Communications, 2016 Dec. 1;7:13500. * Corresponding author

Ø  S. Khurana. The effects of proliferation and DNA damage on hematopoietic stem cell function determine ageing. Developmental Dynamics Dev Dyn. 2016 Jul;245(7):739-50. Review.

Ø  Manesia J., Xu Z., Broekaert D., Boon R., van Vliet A., Vanwelden T., Eelen G., Pascual-Montano A., Maria-Fendt S., Carmeliet G., Carmeliet P., Khurana S.*, Verfaillie C.M.* Highly proliferative primitive fetal liver hematopoietic stem are fueled by oxidative metabolic pathways. Stem Cell Research 2015 Nov 9;15(3):715-721 * Co-corresponding author

Ø  C. Gil-Sanchis, I. Cervelló, S. Khurana, A. Faus, C.M. Verfaillie and C. Simón. Contribution of different bone marrow-derived cell types in endometrial regeneration using an irradiated murine model. Fertility and Sterility Epub March 2015

Ø  S. Raitano, L. Ordovàs, L. De Muynck, W. Guo, I. Espuny-Camacho, M. Geraerts, S. Khurana, K. Vanuytsel, B.I. Tóth, T. Voets, T. Cathomen, P. Vanderhaeghen, P. Van Damme, C.M. Verfaillie. Restoration of Progranulin Expression Rescues Corticogenesis in Frontotemporal Dementia-Derived Induced Pluripotent Stem Cells. Stem Cell Reports. 2015 Jan 13;4(1):16-24.

Ø  K. Vanuytsel, Q. Cai, N. Nair, S. Khurana, S Shetty, J.R. Vermeesch, L. Ordovas and C.M. Verfaillie. FANCA Knockout in Human Embryonic Stem Cells Causes a Severe Growth Disadvantage. Stem Cell Res. 2014 Sep;13(2):240-50.

Ø  S. Khurana*, Alessia Melacarne, Rana Yadek, Sarah Schouteden, Catherine Verfaillie. SMAD dependent BMP signaling regulates CXCL12 expression in adult bone marrow stromal cells. Accepted in Stem Cells June 2014. * Corresponding author

Ø  S. Khurana*, C. Joseph, L. Margamuljana, S. Buckley, S. Schouteden, C. M. Verfaillie. Tfpi improves hematopoietic stem cell migration and homing by decreasing CD26 activity through Glypican 3. Blood. 2013 Apr 4;121(14):2587-95. Plenary paper * As co-corresponding author

Ø  A. M. Schaap-Oziemlak, S. Schouteden, S. Khurana, C. M. Verfaillie. Wnt5a does not support hematopoiesis in stroma-free, serum-free cultures. PLoS One. 2013, 8(1): e53669.

Ø  S. Khurana*, S. Buckley, S. Schouteden, S. Ekker, A. Petryk, M. Delforge, A. Zwijsen, C.M. Verfaillie. A novel role of BMP4 in adult hematopoietic stem and progenitor cell homing via Smad independent regulation of Integrin-α4 expression. Blood. 2013 Jan 31;121(5):781-90. * As co-corresponding author

Ø  S. Khurana, A. Kumar, A. Mukhopadhyay. Hepatocyte Nuclear Factor (HNF)-4α induces transdifferentiation of hematopoietic stem cells into hepatocytes. J Biol Chem. 2010 Feb 12;285(7):4725-31.

Ø  S. Khurana and A. Mukhopadhyay. Hematopoietic Progenitors from Early Murine Fetal Liver Possess Hepatic Differentiation Potential. Am J Pathol. 2008 Dec;173(6):1818-27.

Ø  S. Khurana and A. Mukhopadhyay. In vitro transdifferentiation of adult hematopoietic stem cells: an alternate source engraftable hepatocytes. J Hepatol. 2008 Dec;49(6):998-1007. (Cover page article)

Ø  S. Khurana and A. Mukhopadhyay. Characterization of the potential subpopulation of bone marrow cells involved in the repair of injured liver tissue. Stem Cells. 2007 Jun;25(6):1439-47.

Ø  S. Rentala, M.M. Sagar Balla, S. Khurana, A. Mukhopadhyay . MDR1 gene expression enhances long-term engraftibility of cultured bone marrow cells. Biochem Biophys Res Commun. 2005 Sep 30;335(3):957-64.



Ø  TFPI in “Maintenance/expansion of hematopoietic stem cells”. US Patent publication no. US 2011/0311492 A1



Ø  N. Nagananda, A.M. Ali, I.M. Roy, C.M. Verfaillie, S. Khurana. Physico-chemical properties of the stem cell niche. In A. Muykhopadhyay ed. Regenerative Medicine, Springer India Pvt. Ltd. In Press.  

Ø  S. Khurana, S. Bhaskar and A. Mukhopadhyay. Laboratory practice for the production of polyclonal and monoclonal antibodies. In A. Varma, R Oelmuller, eds. Advanced techniques in soil microbiology, Springer-verlag Berlin Heidelberg, 2007:73-91.

Ø  S. Khurana, S. Bhaskar and A. Mukhopadhyay . Modern techniques for analyzing immunological responses. In A. Varma, R Oelmuller, eds. Advanced techniques in soil microbiology, Springer-verlag Berlin Heidelberg, 2007:92-109.