Publications and Presentations

(For guidance check:

  • Kidiyoor GR, Kumar A, Foiani M. ATR-mediated regulation of nuclear and cellular plasticity. DNA Repair (Amst). 2016; 44:143-50.
  • Awasthi P, Foiani M and Kumar A. ATM and ATR signaling at a glance. J Cell Sci. 2015; 128(23):4255-62.
  • Agarwal S, Tiwari SK, Seth B, Yadav A, Singh A, Mudawal A, Chauhan LK, Gupta SK, Choubey V, Tripathi A, Kumar A , Ray RS, Shukla S, Parmar D, Chaturvedi RK. Activation of autophagic flux against

        xenoestrogen Bisphenol- A induced hippocampal neurodegeneration viaAMPK/mTOR pathways. J Biol Chem. 2015; 290(34):21163-84.

  • Pérez-García V, Redondo-Muñoz J, Kumar A, Carrera AC. Cell activation-induced ?phosphoinositide 3-kinase alpha/beta dimerization regulates PTEN activity. Mol Cell Biol. 2014; 34(18): 3359-3373.
  • Kumar A, Mazzanti M, Mistrik M, Kosar M, Beznoussenko GV, Mironov AA, Garre M, ?Parazzoli D, Shivashankar GV, Scita G, Bartek J, Foiani M. 2014. ATR mediates a mechanical checkpoint at the nuclear envelope in response to mechanical stress. Cell. 2014; 158(3): 633–646.
  • Parrillas V, Muñoz LM, López-Holgado B, Kumar A, Lucas P, Rodríguez-Frade JM, Malumbres M, Carrera AC, vanWely KHM, and Mellado M. Suppressor of cytokine signaling 1 blocks mitosis in human melanoma cells. Cellular and Molecular Life Sciences. 2013; 70(3):545-58.
  • Rodrigo Bermejo, Amit Kumar and Marco Foiani. Preserving the genome by regulating chromatin association to the nuclear envelope. Trends in Cell Biology. 2012; 22 (9); 465- 473.
  • Kumar A*, Redondo Munopz J*, Perez Garcia V*, Cortes I, Chagoyen M and Carrera AC. Nuclear but not cytosolic phosphoinositide 3-kinase beta plays an essential function in cell survival. Mol Cell Biol, 2011; 31; 2122-2133. *equal contribution
  • Kumar A, Fernadez-Capetillo O and Carrera AC. Nuclear  phosphoinositide  3- kinase beta controls double stand break DNA repair. Proc Natl Aci Sci USA. 2010; 107; 7491- 7496.
  • Marqués M*, Kumar A*, Poveda AM, Zuluaga S, Hernández C, Jackson S, Pasero P and Carrera AC. Specific function of phosphoinositide 3-kinase beta in the control of DNA replication. Proc Natl Aci Sci USA. 2009; 106; 7525-7530. *equal contribution
  • Marqués M, Kumar A, Cortés I, Gonzalez-García A, Hernández C, Moreno-Ortiz MC and Carrera AC. Phosphoinositide 3-kinases p110alpha and p110beta regulate cell cycle entry, exhibiting distinct activation kinetics in G1 phase. Mol Cell Biol. 2008; 28; 2803- 2814.
  • Alcázar I, Marqués M, Kumar A, Hirsch E, Wymann M, Carrera AC, Barber DF. Phosphoinositide   3-kinase   gamma   participates   in   T   cell   receptor-induced   T   cell activation. J Exp Med. 2007; 204; 2977-2987.
  • Kumar A, Carrera AC. New functions for PI3K in the control of cell division. Cell Cycle. 2007; 6; 1696-1698.
  • García Z, Silió V, Marqués M, Cortés I, Kumar A, Hernández C, Checa AI, Serrano A and Carrera AC. A PI3K activity-independent function of p85 regulatory subunit in control of mammalian cytokinesis. EMBO J. 2006; 25; 4740-4751.
  • Kumar A, Marqués M, Carrera AC. Phosphoinositide 3-kinase activation in late G1 is required for c-Myc stabilization and S phase entry. Mol Cell Biol. 2006; 26; 9116-9125.
  • García Z, Kumar A, Marqués M, Cortés I and Carrera AC. Phosphoinositide 3- kinase controls early and late events in mammalian cell division. EMBO J. 2006; 25; 655-661.
  • Kumar A*, Vaid A*, Syin C and Sharma P. PfPKB, a novel protein kinase B-like enzyme from Plasmodium falciparum:  I.  Identification,  characterization,  and  possible role in parasite development.  J Biol Chem. 2004; 279; 24255-24264. *equal contribution